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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LBR All Species: 35.15
Human Site: Y608 Identified Species: 55.24
UniProt: Q14739 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14739 NP_002287.2 615 70703 Y608 K Y C Q R V P Y R I F P Y I Y
Chimpanzee Pan troglodytes XP_514234 615 70705 Y608 K Y R Q R V P Y R I F P Y I Y
Rhesus Macaque Macaca mulatta XP_001094360 615 70652 Y608 K Y C Q R V P Y R I F P Y I Y
Dog Lupus familis XP_547512 618 70479 Y611 K Y C Q R V P Y R I F P Y V Y
Cat Felis silvestris
Mouse Mus musculus Q3U9G9 626 71422 Y619 K Y C Q R V P Y R I F P Y I Y
Rat Rattus norvegicus O08984 620 70706 Y613 K Y C Q R V P Y R I F P Y I Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514211 617 70577 Y610 K Y C Q C V P Y R I F P Y I Y
Chicken Gallus gallus P23913 637 73480 Y601 R Y C Q R V P Y T H I S L H L
Frog Xenopus laevis Q7ZXH1 473 54804 Y466 L Y T S A V P Y R L L P G L F
Zebra Danio Brachydanio rerio Q7SXF1 478 55171
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MLV1 741 83167 R733 Q R Y S T Q V R S Y I L P R V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786536 578 65964 Y571 K Y C A T V K Y R I I P Y I Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDR4 369 41895
Baker's Yeast Sacchar. cerevisiae P32462 438 50597
Red Bread Mold Neurospora crassa P38670 490 54704
Conservation
Percent
Protein Identity: 100 99 98.2 82.3 N.A. 78.7 79.5 N.A. 78.1 65.4 30.4 29.9 N.A. 23 N.A. N.A. 44.2
Protein Similarity: 100 99.8 99.3 89.4 N.A. 88 87.4 N.A. 87.3 77.3 45.8 46.1 N.A. 38.7 N.A. N.A. 59.1
P-Site Identity: 100 93.3 100 93.3 N.A. 100 100 N.A. 93.3 46.6 40 0 N.A. 0 N.A. N.A. 73.3
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 93.3 53.3 60 0 N.A. 6.6 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 28.2 30.5 20.6
Protein Similarity: N.A. N.A. N.A. 40.9 43.2 34.8
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 0 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 54 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 47 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 54 20 0 0 47 0 % I
% Lys: 54 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 0 0 0 0 0 0 0 7 7 7 7 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 60 0 0 0 0 60 7 0 0 % P
% Gln: 7 0 0 54 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 7 7 0 47 0 0 7 60 0 0 0 0 7 0 % R
% Ser: 0 0 0 14 0 0 0 0 7 0 0 7 0 0 0 % S
% Thr: 0 0 7 0 14 0 0 0 7 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 67 7 0 0 0 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 67 7 0 0 0 0 67 0 7 0 0 54 0 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _